Relationship of Hypoalbuminemia to Multiple Clinical Factors in Hemodialysis Patients
Identifieur interne : 000244 ( Psycho/Analysis ); précédent : 000243; suivant : 000245Relationship of Hypoalbuminemia to Multiple Clinical Factors in Hemodialysis Patients
Auteurs : K. Schiro-Harvey ; R. Diamond ; A. Jones ; J. Buss [États-Unis]Source :
- Hemodialysis International [ 1492-7535 ] ; 2004-01.
Abstract
Research shows that low albumin is correlated with higher morbidity and mortality in the dialysis population. The reasons for this are multi‐factorial and may be related to inadequate protein intake, infection and sepsis, inadequate dialysis, or catabolism of uremia. USRDS data show that ESRD Network 16 tends to have lower albumins compared to other ESRD Networks. Objective: To evaluate albumin status of HD patients at Puget Sound Kidney Centers, Everett, WA (ESRD Network 16) and identify potential factors that may put patients at risk of hypoalbuminemia. Methods: Clinical and biochemical data were collected for 3 months on 221 HD patients. Data included serum albumin (bromcresol purple), calcium, phosphorus, CO2, Hct, % saturation, ferritin, PTH, BUN, Kt/V, URR, nPCR, hours of HD treatment, interdialytic fluid weight gains, DW changes, incidence of infection and hospitalization, catheter use for dialysis access, presence of diabetes and other co‐morbidities, dialyzer reuse, social/psychological status, and use of nutrition supplements. All biochemical data were collected after the longest interdialytic period and analyzed at the same reference laboratory. Data were averaged for each patient for the 3 months and correlations between parameters were determined using Chi‐square analysis. Results: 25% of all patients had albumins <3.2 g/dL (reference range for normal population 3.5–5.0 g/dL). Patients with lower albumins were significantly more likely to have DM (p < 0.02), use catheters for HD access (p < 0.001), had infections during the previous month (p < 0.001), been hospitalized during the previous month (p < 0.002), have co‐morbid issues (p < 0.001), and use nutrition supplements (p < 0.002). No other factors were significantly correlated with lower albumin. Conclusion: Factors other than nutrition seem to be related to hypoalbuminemia. This study has prompted improved protocols for catheter care and use, infection control, and early intervention for nutrition supplement use. Increased screening and monitoring at‐risk patients (those with diabetes and other co‐morbid conditions) has resulted in improved patient care.
Url:
DOI: 10.1111/j.1492-7535.2004.0085bl.x
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 001449
- to stream Istex, to step Curation: 001449
- to stream Istex, to step Checkpoint: 001E03
- to stream Main, to step Merge: 005B71
- to stream Main, to step Curation: 005725
- to stream Main, to step Exploration: 005725
- to stream Psycho, to step Extraction: 000244
Links to Exploration step
ISTEX:32CE81AE2763C7C15E1620304712BBEA1953C02ELe document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Relationship of Hypoalbuminemia to Multiple Clinical Factors in Hemodialysis Patients</title>
<author><name sortKey="Schiro Arvey, K" sort="Schiro Arvey, K" uniqKey="Schiro Arvey K" first="K." last="Schiro-Harvey">K. Schiro-Harvey</name>
</author>
<author><name sortKey="Diamond, R" sort="Diamond, R" uniqKey="Diamond R" first="R." last="Diamond">R. Diamond</name>
</author>
<author><name sortKey="Jones, A" sort="Jones, A" uniqKey="Jones A" first="A." last="Jones">A. Jones</name>
</author>
<author><name sortKey="Buss, J" sort="Buss, J" uniqKey="Buss J" first="J." last="Buss">J. Buss</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:32CE81AE2763C7C15E1620304712BBEA1953C02E</idno>
<date when="2004" year="2004">2004</date>
<idno type="doi">10.1111/j.1492-7535.2004.0085bl.x</idno>
<idno type="url">https://api.istex.fr/ark:/67375/WNG-C9W4WJMG-G/fulltext.pdf</idno>
<idno type="wicri:Area/Istex/Corpus">001449</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">001449</idno>
<idno type="wicri:Area/Istex/Curation">001449</idno>
<idno type="wicri:Area/Istex/Checkpoint">001E03</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">001E03</idno>
<idno type="wicri:doubleKey">1492-7535:2004:Schiro Arvey K:relationship:of:hypoalbuminemia</idno>
<idno type="wicri:Area/Main/Merge">005B71</idno>
<idno type="wicri:Area/Main/Curation">005725</idno>
<idno type="wicri:Area/Main/Exploration">005725</idno>
<idno type="wicri:Area/Psycho/Extraction">000244</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main">Relationship of Hypoalbuminemia to Multiple Clinical Factors in Hemodialysis Patients</title>
<author><name sortKey="Schiro Arvey, K" sort="Schiro Arvey, K" uniqKey="Schiro Arvey K" first="K." last="Schiro-Harvey">K. Schiro-Harvey</name>
<affiliation><wicri:noCountry code="subField">Everett</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Diamond, R" sort="Diamond, R" uniqKey="Diamond R" first="R." last="Diamond">R. Diamond</name>
<affiliation><wicri:noCountry code="subField">Everett</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Jones, A" sort="Jones, A" uniqKey="Jones A" first="A." last="Jones">A. Jones</name>
<affiliation><wicri:noCountry code="subField">Everett</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Buss, J" sort="Buss, J" uniqKey="Buss J" first="J." last="Buss">J. Buss</name>
<affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Northwest Renal Network 16, Seattle, WA</wicri:regionArea>
<placeName><region type="state">Washington (État)</region>
</placeName>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j" type="main">Hemodialysis International</title>
<title level="j" type="alt">HEMODIALYSIS INTERNATIONAL</title>
<idno type="ISSN">1492-7535</idno>
<idno type="eISSN">1542-4758</idno>
<imprint><biblScope unit="vol">8</biblScope>
<biblScope unit="issue">1</biblScope>
<biblScope unit="page" from="102">102</biblScope>
<biblScope unit="page" to="103">103</biblScope>
<biblScope unit="page-count">100</biblScope>
<publisher>Blackwell Science Inc</publisher>
<pubPlace>Oxford, UK; Malden, USA</pubPlace>
<date type="published" when="2004-01">2004-01</date>
</imprint>
<idno type="ISSN">1492-7535</idno>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">1492-7535</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Research shows that low albumin is correlated with higher morbidity and mortality in the dialysis population. The reasons for this are multi‐factorial and may be related to inadequate protein intake, infection and sepsis, inadequate dialysis, or catabolism of uremia. USRDS data show that ESRD Network 16 tends to have lower albumins compared to other ESRD Networks. Objective: To evaluate albumin status of HD patients at Puget Sound Kidney Centers, Everett, WA (ESRD Network 16) and identify potential factors that may put patients at risk of hypoalbuminemia. Methods: Clinical and biochemical data were collected for 3 months on 221 HD patients. Data included serum albumin (bromcresol purple), calcium, phosphorus, CO2, Hct, % saturation, ferritin, PTH, BUN, Kt/V, URR, nPCR, hours of HD treatment, interdialytic fluid weight gains, DW changes, incidence of infection and hospitalization, catheter use for dialysis access, presence of diabetes and other co‐morbidities, dialyzer reuse, social/psychological status, and use of nutrition supplements. All biochemical data were collected after the longest interdialytic period and analyzed at the same reference laboratory. Data were averaged for each patient for the 3 months and correlations between parameters were determined using Chi‐square analysis. Results: 25% of all patients had albumins <3.2 g/dL (reference range for normal population 3.5–5.0 g/dL). Patients with lower albumins were significantly more likely to have DM (p < 0.02), use catheters for HD access (p < 0.001), had infections during the previous month (p < 0.001), been hospitalized during the previous month (p < 0.002), have co‐morbid issues (p < 0.001), and use nutrition supplements (p < 0.002). No other factors were significantly correlated with lower albumin. Conclusion: Factors other than nutrition seem to be related to hypoalbuminemia. This study has prompted improved protocols for catheter care and use, infection control, and early intervention for nutrition supplement use. Increased screening and monitoring at‐risk patients (those with diabetes and other co‐morbid conditions) has resulted in improved patient care.</div>
</front>
</TEI>
<affiliations><list><country><li>États-Unis</li>
</country>
<region><li>Washington (État)</li>
</region>
</list>
<tree><noCountry><name sortKey="Diamond, R" sort="Diamond, R" uniqKey="Diamond R" first="R." last="Diamond">R. Diamond</name>
<name sortKey="Jones, A" sort="Jones, A" uniqKey="Jones A" first="A." last="Jones">A. Jones</name>
<name sortKey="Schiro Arvey, K" sort="Schiro Arvey, K" uniqKey="Schiro Arvey K" first="K." last="Schiro-Harvey">K. Schiro-Harvey</name>
</noCountry>
<country name="États-Unis"><region name="Washington (État)"><name sortKey="Buss, J" sort="Buss, J" uniqKey="Buss J" first="J." last="Buss">J. Buss</name>
</region>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/Psycho/Analysis
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000244 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Psycho/Analysis/biblio.hfd -nk 000244 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Sante |area= SrasV1 |flux= Psycho |étape= Analysis |type= RBID |clé= ISTEX:32CE81AE2763C7C15E1620304712BBEA1953C02E |texte= Relationship of Hypoalbuminemia to Multiple Clinical Factors in Hemodialysis Patients }}
This area was generated with Dilib version V0.6.33. |